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Relationships among tau burden, atrophy, age, and naming in the aphasic variant of Alzheimer’s disease

September 9, 2021 Abstract Introduction Examination of pathologic, anatomic, and cognitive relationships has been limited in primary progressive aphasia (PPA) with underlying Alzheimer’s disease (AD) neuropathology. Methods Spatial relationships between tau...

Diet, psychosocial stress, and Alzheimer’s disease–related neuroanatomy in female nonhuman primates

May 14, 2021 Abstract Introduction Associations between diet, psychosocial stress, and neurodegenerative disease, including Alzheimer’s disease (AD), have been reported, but causal relationships are difficult to determine in human studies. Methods We used...

Neuropsychological profile of amyloid‐positive versus amyloid‐negative amnestic Mild Cognitive Impairment

May 6, 2021 Introduction Patients diagnosed with amnestic mild cognitive impairment (aMCI) are at high risk of progressing to dementia. It became possible, through the use of biomarkers, to diagnose those patients with aMCI who have Alzheimer’s disease. However,...

Self‐reported obstructive sleep apnea, amyloid and tau burden, and Alzheimer’s disease time‐dependent progression

February 28, 2021 Abstract Introduction Obstructive sleep apnea (OSA) is associated with Alzheimer’s disease (AD) biomarkers in cognitively normal (CN) and mild cognitive impaired (MCI) participants. However, independent and combined effects of OSA, amyloid beta...