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Relationships among tau burden, atrophy, age, and naming in the aphasic variant of Alzheimer’s disease

September 9, 2021 Abstract Introduction Examination of pathologic, anatomic, and cognitive relationships has been limited in primary progressive aphasia (PPA) with underlying Alzheimer’s disease (AD) neuropathology. Methods Spatial relationships between tau...

Reliable change in neuropsychological test scores is associated with brain atrophy in older adults

June 11, 2021 The reliable change index (RCI) is a commonly used method for interpreting change in neuropsychological test scores over time. However, the RCI is a psychometric method that, to date, has not been validated against neuroanatomical changes. Longitudinal...