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Insomnia symptom severity and cognitive performance: Moderating role of APOE genotype

July 31, 2021 Abstract Introduction We evaluated whether insomnia symptom severity was associated with cognitive function, and whether this relationship was modified by biomarkers associated with Alzheimer’s disease risk. Methods We examined insomnia symptoms...

Reliable change in neuropsychological test scores is associated with brain atrophy in older adults

June 11, 2021 The reliable change index (RCI) is a commonly used method for interpreting change in neuropsychological test scores over time. However, the RCI is a psychometric method that, to date, has not been validated against neuroanatomical changes. Longitudinal...

How impaired is too impaired? Exploring futile neuropsychological test patterns as a function of dementia severity and cognitive screening scores

March 4, 2021 Some older adults cannot meaningfully participate in the testing portion of a neuropsychological evaluation due to significant cognitive impairments. There are limited empirical data on this topic. Thus, the current study sought to provide an operational...