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Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes

July 1, 2021 Abstract Introduction Apathy adversely affects prognosis and survival of patients with frontotemporal dementia (FTD). We test whether apathy develops in presymptomatic genetic FTD, and is associated with cognitive decline and brain atrophy. Methods...

73| Neuropsych Bite: Acute Disseminated Encephalomyelitis (ADEM) – With Dr. Lana Harder

July 1, 2021 Acute disseminated encephalomyelitis (ADEM) is a rare, monophasic autoimmune condition affecting the brain and spinal cord. The symptoms of ADEM can be variable, given that lesions can present in multiple areas of the central nervous system. ADEM shares...

Reliable change in neuropsychological test scores is associated with brain atrophy in older adults

June 11, 2021 The reliable change index (RCI) is a commonly used method for interpreting change in neuropsychological test scores over time. However, the RCI is a psychometric method that, to date, has not been validated against neuroanatomical changes. Longitudinal...

Consecutive and temporally distant perseverations after right brain damage: A prospective study.

May 14, 2021 Objective: Right brain-damaged patients may show omissions and/or additional marks in target cancellation. The latter is classified as perseverative behavior and has been attributed to defective response inhibition or attentional disengagement deficit....