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Insomnia symptom severity and cognitive performance: Moderating role of APOE genotype

July 31, 2021 Abstract Introduction We evaluated whether insomnia symptom severity was associated with cognitive function, and whether this relationship was modified by biomarkers associated with Alzheimer’s disease risk. Methods We examined insomnia symptoms...

Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes

July 1, 2021 Abstract Introduction Apathy adversely affects prognosis and survival of patients with frontotemporal dementia (FTD). We test whether apathy develops in presymptomatic genetic FTD, and is associated with cognitive decline and brain atrophy. Methods...

A blood screening tool for detecting mild cognitive impairment and Alzheimer’s disease among community‐dwelling Mexican Americans and non‐Hispanic Whites: A method for increasing representation of diverse populations in clinical research

June 11, 2021 Abstract Introduction Representation of Mexican Americans in Alzheimer’s disease (AD) clinical research has been extremely poor. Methods Data were examined from the ongoing community-based, multi-ethnic Health & Aging Brain among Latino Elders...

Diet, psychosocial stress, and Alzheimer’s disease–related neuroanatomy in female nonhuman primates

May 14, 2021 Abstract Introduction Associations between diet, psychosocial stress, and neurodegenerative disease, including Alzheimer’s disease (AD), have been reported, but causal relationships are difficult to determine in human studies. Methods We used...

Identification of undiagnosed dementia cases using a web‐based pre‐screening tool: The MOPEAD project

April 23, 2021 Abstract Introduction Innovative patient engagement models are required to identify people with prodromal and mild Alzheimer’s disease who are “hidden” in their communities and not normally found in a memory clinic setting. Methods A marketing...